Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: a systematic review and meta-analysis of randomized controlled trials
The American Journal of Clinical Nutrition
Reviewed guidance
Psyllium for hypercholesterolemia (high cholesterol)
A systematic review and meta-analysis of randomized trials found psyllium can modestly reduce LDL cholesterol. Evidence applies to oral psyllium fiber used over time, not immediate symptom relief, and does not establish prevention of heart attack or stroke or replacement of prescribed lipid-lowering therapy.
What this means
May modestly lower LDL cholesterol as an adjunct to dietary and medical management; hypercholesterolemia itself usually causes no symptoms.
How to use it: Use only as directed on the product label, mix with sufficient liquid, and separate it from medicines when the label or clinician advises. Discuss use with a clinician and recheck lipids as advised; do not stop prescribed treatment.
Safety & cautions
Do not take dry or with too little liquid. Stop and seek care for trouble swallowing, chest pain, vomiting, severe abdominal pain, or inability to pass stool or gas. Ask a clinician first if you have swallowing difficulty, bowel narrowing or obstruction, or take medicines that may be affected by fiber.
Get medical care for symptoms that are severe, last longer than expected, get worse, or otherwise concern you.
Household preparations
Practical ways to use the ingredient may not provide the same form or amount discussed in the evidence.
Evidence transparency